Jurnal Farmasi Sains dan Praktis
Vol 9 No 2 (May-August 2023)

PHYSICAL STABILITY TEST HAIR TONIC COMBINATION Cinnamon (Cinnamomum burmanii) ESSENTIAL OIL AND VCO (VIRGIN COCONUT OIL) WITH CYCLING TEST METHOD AND IRRITATION TEST ON THE RABBIT

Junvidya Heroweti (Department of Pharmacology and clinical pharmacy, Universitas Wahid Hasyim, Semarang, Indonesia, 50236)
Danang Novianto Wibowo (Department of Pharmaceuticals and Pharmaceutical Technology, Universitas Wahid Hasyim, Semarang 50236, Indonesia)
Arini Najikhatal Ulya (Pharmacy Study Program, Faculty of Pharmacy, Universitas Wahid Hasyim, Semarang 50236, Indonesia)
Desmita Linda (Pharmacy Study Program, Faculty of Pharmacy, Universitas Wahid Hasyim, Semarang 50236, Indonesia)



Article Info

Publish Date
14 May 2023

Abstract

Cinnamon (Cinnamomum burmanii) and VCO (Virgin Coconut Oil) essential oils contain cinnamaldehyde and lauric acid which have potential for hair growth, they can affect the physical stability of hair tonic preparations. This study aims to determine the physical stability and determine the effect of the irritation effect on hair tonic preparations of a combination of cinnamon essential oil and VCO. Cinnamon essential oil hair tonic preparations were made with a concentration of 1% (F1), 3% (F2), and 5% (F3) and then tested for physical characteristics including organoleptic tests, homogeneity, pH, density test, and viscosity. Evaluation of physical stability was carried out using the cycling test method. Data were statistically analyzed using One Way Anova. The results of the irritation test were analyzed descriptively using the primary irritation index obtained from the appearance of erythema and edema on the rabbit's skin. Observation of the physical stability test on organoleptic and homogeneity showed that formula I had a cloudy white color, a characteristic cinnamon aroma, a slightly thick liquid, and was homogeneous; formula 2 and 3 has a clear color, characteristic of cinnamon aroma, slightly viscous and homogeneous liquid; stable pH in formula 2; stable density in formulas 1, 2 and 3; and stable viscosity in formulas 2 and 3. The results of the hair tonic irritation test showed that the primary irritation index for F1, F2, and F3 was 0.0; 0.3; 0.3 and it can be concluded that F2 and F3 can irritate with very mild categories.

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Journal Info

Abbrev

pharmacy

Publisher

Subject

Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Farmasi Sains dan Praktis aims to serve the updated scientific knowledge for international researchers in pharmaceutical sciences. Jurnal Farmasi Sains dan Praktis (JFSP) publishes review article, original article, as well as short communication in the all scopes of Pharmaceutical Science ...