Jurnal Farmasi Sains dan Komunitas
Vol 20, No 1 (2023)

The Association Between Medication Adherence and Blood Pressure Control in End-Stage Renal Disease Patients with Hemodialysis

Pande Made Desy Ratnasari (Bachelor of Pharmacy Study Program, Sekolah Tinggi Farmasi Mahaganesha, East Barito Tukad Street, 80226, Renon, Denpasar-Bali)
Ketut Tia Pran Anggar Yani (Bachelor of Pharmacy Study Program, Sekolah Tinggi Farmasi Mahaganesha, East Barito Tukad Street, 80226, Renon, Denpasar-Bali)
Agustina Nila Yuliawati (Bachelor of Pharmacy Study Program, Sekolah Tinggi Farmasi Mahaganesha, East Barito Tukad Street, 80226, Renon, Denpasar-Bali)
Anak Agung Ngurah Putra Riana Prasetya (Bachelor of Pharmacy Study Program, Sekolah Tinggi Farmasi Mahaganesha, East Barito Tukad Street, 80226, Renon, Denpasar-Bali)



Article Info

Publish Date
31 May 2023

Abstract

End-Stage Renal Disease (ESRD) is a severe kidney disorder that contributes to an increased risk of mortality in the world. This condition is often related with hypertension. Low medication adherence was affecting uncontrolled blood pressure in ESRD. The research aimed to analyze the association between medication adherence and blood pressure control in ESRD patients. This cross-sectional study with 77 respondents was conducted in September 2020 at the Dialysis Unit of the Private Hospital “X” Buleleng Bali by purposive sampling technique. The respondents must be ≥18 years, diagnosed with ESRD and hypertension, underwent hemodialysis (HD) twice a week, received the same antihypertensive for 3 months, have complete medical record data, and signed the informed consent form. Patients with cognitive impairment, unable to communicate, pregnant or breastfeeding, and received the Erythropoiesis Stimulating Agent (ESA) treatment were excluded. Kruskal-Wallis test was used in data analysis. Most of the patients were 65 years (80.52%), male (70.13%), primary education (57.14%), without complications (57.1%), and duration of illness 5 years (89.61%). Patients were in the high adherence (61.04%) and 66.23% of patients had uncontrolled blood pressure. The association between medication adherence and blood pressure control was not significant (p=0.478). However, these results show that high medication adherence could impact on good blood pressure control.

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Journal Info

Abbrev

JFSK

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical ...