<![CDATA[This research compares strategies for identifying diabetic retinopathy (DR) using fundus image and discusses the efficiency of various image pre-processing techniques to enhance the quality of fundus images. Fundus images in medical image processing often suffer from non-uniform lighting, low contrast, and noise issues, which necessitate image pre-processing to enhance their quality. The study evaluates the effectiveness of several optimization techniques in selecting the best technique for identifying DR. One of the image pre-processing techniques compared in the study involves comparing negative images, dark contrast stretch, light contrast stretch, and partial contrast stretch, which are then evaluated using standard performance metrics such as NIQE, PNSR, MSE, and entropy. The results are further optimized using the Cuckoo Search Algorithm. The proposed technique produces better image quality improvements in several performance metrics, such as MSE, NIQE, PSNR, and entropy. Bright Contrast Stretch outperforms other techniques in NIQE Mean 5.2850, Entropy 5.0193, NIQE Standard deviation 0.2261, and Entropy 0.2612.]]>
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