Pengembangan Formula Spray Gel Ekstrak Etanol Daun Komba- Komba (Eupatorim Odoratum) Sebagai Kandidat Repellent

Michrun Nisa (Sekolah Tinggi Ilmu Farmasi Makassar)
Irmayani Irmayani (Sekolah Tinggi Ilmu Farmasi Makassar)
Sweety Dwy Sarty (Sekolah Tinggi Ilmu Farmasi Makassar)

Jurnal Farmasi dan Sains Indonesia (JFSI)
Vol 5 No 1 (2022)

Repellent is an insecticide that is used to protect the skin from mosquito bites. Spray gel is a form of developing gel preparations applied through a pump spray. Ethanol extract of komba – komba (Eupatorium odoratum) leaves with a concentration of 7% has mosquito repellent activity because it contains compounds that are toxic to mosquitoes. 100% protection at the 1st hour followed by 73% at the 6th hour. This study aims to formulate the ethanolic extract of komba-komba leaves in the form of a spray gel with a variation of the gelling agent carbopol 940: HPMC, namely, 0.5%: 0.25%; 1% : 0.5% ; and 1.5% : 0.75%. Physical evaluation of the preparation includes organoleptic test, pH test, viscosity test, spray pattern test and dry time. The evaluation results show that formula 2 meets the param eters of the physical properties of the spray gel preparation