Journal of Pharmaceutical and Sciences.
JPS Volume 6 Nomor 1 (2023)

ANALISIS BERBAGAI METODE IDENTIFIKASI ISOFLAVON: LITERATUR REVIEW

Vriezka Mierza (Universitas Singaperbangsa Karawang, Jl. HS. Ronggo Waluyo, Telukjambe Timur, Karawang, Jawa Barat, Indonesia)
Fitri Aida (Universitas Singaperbangsa Karawang, Jl. HS. Ronggo Waluyo, Telukjambe Timur, Karawang, Jawa Barat, Indonesia)
Hajar Hartati (Universitas Singaperbangsa Karawang, Jl. HS. Ronggo Waluyo, Telukjambe Timur, Karawang, Jawa Barat, Indonesia)
Herdiana Verliani (Universitas Singaperbangsa Karawang, Jl. HS. Ronggo Waluyo, Telukjambe Timur, Karawang, Jawa Barat, Indonesia)
Nisa Alifia Zahra (Universitas Singaperbangsa Karawang, Jl. HS. Ronggo Waluyo, Telukjambe Timur, Karawang, Jawa Barat, Indonesia)
Rika Valensia (Universitas Singaperbangsa Karawang, Jl. HS. Ronggo Waluyo, Telukjambe Timur, Karawang, Jawa Barat, Indonesia)



Article Info

Publish Date
09 Jan 2023

Abstract

Isoflavone is included in the phytoestrogens, a natural plant substance with a structure similar to 17-β-estradiol. It can bind to estrogen receptors so that isoflavones can prevent or slow down forms of cancer related to Alzheimer's hormones, osteoporosis, and others. Isoflavones are also included in the flavonoids found in fruits such as berries, grapes and are most abundant in soybeans and other nuts. From the literature study that has been conducted, it was found that there are several methods for identifying isoflavone compounds, including HPLC/HPLC, TLC, UV-Vis Spectrophotometry, Mass Spectrophotometry, and others. Of the many types of isoflavones that exist, the most commonly identified isoflavones are genistein and daidzein, which can be found in samples of soybeans, soy milk, and processed tempeh. The isoflavone content identified by each researcher differs in terms of the quantity and type of isoflavone content. This is because in identifying isoflavones, there are factors that influence them. The duration of fermentation has an effect because it is related to the presence of dissolved compounds during the fermentation process, which results in differences in the quantity of isoflavones, besides that the reactive and easily oxidized nature of isoflavones causes isoflavones to bind to other compounds to form new unknown compounds so that isoflavones are no longer identified.

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Journal Info

Abbrev

jps

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...