Analit: Analytical and Environmental Chemistry
Vol 8, No 2 (2023): ANALIT: ANALYTICAL AND ENVIRONMENTAL CHEMISTRY

Validation of Medicinal Chemicals Analysis Methods in Pegel Linu and Rheumatic Herbs using the TLC-UV-Visible Spectrophotometry method

Perdana Priya Haresmita (Universitas Muhammadiyah Magelang)
Arief Kusuma Wardani (Program Studi Farmasi Fakultase Ilmu Kesehatan Universitas Muhammadiyah Magelang)
Diva Laila Ramadhani (Program Studi Farmasi Fakultase Ilmu Kesehatan Universitas Muhammadiyah Magelang)
Dwibara Bayuaji (Program Studi Farmasi Fakultase Ilmu Kesehatan Universitas Muhammadiyah Magelang)
Anna Sa'dia Azri (Program Studi Farmasi Fakultase Ilmu Kesehatan Universitas Muhammadiyah Magelang)
Nindya Yunia Putri (Program Studi Farmasi Fakultase Ilmu Kesehatan Universitas Muhammadiyah Magelang)
Mayla Eka Nadia (Unknown)



Article Info

Publish Date
30 Oct 2023

Abstract

Jamu is a traditional Indonesian medicine. Herbal medicine for rheumatism and “pegal linu” is one of the most widely consumed types of traditional medicinal products by the public, so it is a type of traditional medicinal preparation that is prone to the addition of chemical drugs (BKO). All types of traditional medicines are prohibited from containing isolated or synthetic chemicals with medicinal properties. Samples of rheumatism and “pegal linu” jamu were purchased from Grobogan, Central Java, and Gunungkidul, Yogyakarta. Two samples were purchased from Grobogan, while four samples were purchased from Gunungkidul. The standards used were mefenamic acid, phenylbutazone, and diclofenac sodium. Qualitative analysis was carried out using thin-layer chromatography and quantitative analysis using UV-visible spectrophotometry. Validation of the analytical method is carried out by setting four parameters: linearity, precision, limit of detection, and limit of quantitation. Information about the content of BKO in traditional medicines circulating in the Grobogan and Gunungkidul areas, as well as references to valid analytical methods, will greatly assist the government and academics in educating the public about the dangers of long-term consumption of traditional medicine with BKO. The results showed that three of the six samples contained BKO, and the analytical method was valid.

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Journal Info

Abbrev

analit

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Jurnal Analit merupakan jurnal ilmiah yang berisikan hasil penelitian, dan review. Jurnal ini ditujukan untuk mempublikasikan hasil temuan dalam bidang Kimia Analitik dan Kimia Lingkungan. Jurnal Analit terbit secara berkala, yakni dua kali dalam setahun (April dan ...