<![CDATA[The areca nut plant (Areca catechu L) is a traditional plant that has long been used in traditional medicine for various types of diseases such as a stimulant, stomach disorders, worms, smallpox, cholera, venereal diseases and wounds or skin diseases. One of the factors causing skin infections is the bacteria Staphyloccocus aureus. Areca nut (Areca catechu L.) is a natural ingredient that contains antibacterial compounds, namely phenols, alkaloids, terpenoids, saponins, flavonoids, glycosides and tannins. Objective; to determine the antibacterial activity of an ointment preparation of ethanol extract of areca seeds ((Areca catechu L.) against Staphylococcus aureus. Method; this research used experimental research methods, namely the extract was obtained by maceration method with 96% ethanol, and concentrated using a rotary evaporator. Ethanol extract of seeds areca nut is mixed into the ointment preparation with a concentration of 20%, 30%, and 40%. Results; research shows that the average zone of inhibition in each sample of 20% areca nut extract is 7.86 mm, 30% is 12.23 mm, and 40% is 14.3 mm, positive control is 18.36 mm, negative control is 0 mm. Conclusion; from this research is that the ethanol extract of areca nut seeds can be formulated in ointment preparations with concentrations of 20%, 30%, and 40 % which can inhibit the growth of Staphyloccocus aureus bacteria. The concentration of areca nut ethanol extract which has the strongest antibacterial activity against the growth of Staphyloccocus aureus bacteria is a concentration of 40% with an inhibition zone of 14.3 mm.]]>
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