Jurnal RSMH Palembang
Vol. 4 No. 1 (2023): Jurnal RSMH Palembang

Analysis of Adverse Drug Reaction of Favipiravir in COVID-19 Patients in Dr. Mohammad Hoesin General Hospital Palembang

Delita, Sari (Unknown)
Mira Yunita (Unknown)
Lucia Shinta Ratnaningtyas (Unknown)
Anggi Setyarini (Unknown)
Avega Wahyuningrum (Unknown)



Article Info

Publish Date
13 Sep 2023

Abstract

The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Due to its heterogeneous disease severity and rapid transmission, the use of antiviral and immunomodulator drugs is crucial. Favipiravir, an antivirus, can treat SARS-CoV-2 due to its action on RNA Genome ACE2 receptor, therefore halting the viral replication. However, Adverse Drug Reactions (ADRs) monitoring of Favipiravir is recommended. The study design is a descriptive cross-sectional approach with prospective sampling. The study was held in May-July 2021 and aimed to determine the adverse effects of Favipiravir in confirmed COVID-19 patients in Dr. Mohammad Hoesin General Hospital Palembang. Adverse events such as gastrointestinal symptoms (nausea, vomiting, and decreased appetite) occurred in 2 of 170 patients (1.18%). Several side effects, such as an elevated liver enzyme, leukopenia, neutropenia, hyperuricemia, and increased triglyceride levels, cannot be assessed due to a lack of laboratory results before and after Favipiravir administration. Other side effects such as skin rash, asthma, rhinitis, nasopharyngeal pain, and oropharyngeal pain, were not found in the study.

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Journal Info

Abbrev

JRP

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

JRP covers the major topics like Internal Medicine, Obstetric and Gynecology, Pediatric, Surgery, Ear Nose Throat, Neurology, Ophthalmology, Dermatovenerology, Anesthesia and Reanimation, Radiology, Pathology Anatomy, Clinical Pathology, Community Enpowerment, Manajemen of Hospital, Community ...