Jurnal Ilmiah Farmasi Akademi Farmasi Jember
Vol 6, No 1 (2023): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER

EVALUASI SIFAT FISIK TABLET FLOATING FUROSEMIDE DENGAN MATRIKS CARBOPOL

ASA FALAHI (AKADEMI FARMASI JEMBER)



Article Info

Publish Date
31 Jul 2023

Abstract

Furosemide is a sulfonamide-derived diuretic drug which is an alternative treatment for heart failure. Furosemide was made into slow-release tablets to improve the criteria for poor furosemide and maximize its absorption in the stomach. The purpose of this study was to determine whether floating furosemide tablets with a concentration of 23% carbopol matrix could meet the requirements for evaluating the physical properties of tablets compared theoretically with the literatur. The research design used was pre-experimental. In this study, the results of the weight uniformity test showed that there were no deviations from column A and column B, tablet hardness test with an average of 5.4 kg, tablet friability test with a % friability value of 0.08%, floating lag time test with an average time of 184 seconds, and the floating duration time test is with an average time of 8 hours. From the research data, it can be concluded that the floating furosemide tablet with a carbopol matrix concentration of 23% fulfills all evaluations of the physical properties of the tablet

Copyrights © 2023






Journal Info

Abbrev

jurnal_ilmiah_farmasi

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmiah Farmasi Akademi Farmasi Jember merupakan Jurnal yang menampung artikel ilmiah hasil penelitian di seluruh bidang Farmasi, seperti Farmasi Bahan Alam, Kimia Farmasi, Farmasetika, Farmasi Klinis, Farmasi Komunitas, dan bidang farmasi ...