<![CDATA[Skin cancer, one of the most critical forms of cancer, required early detection and documentation for efficient treatment, especially as certain types are fatal. In this study, an artificial neural network (ANN) was utilized to discover and index diverse melanomas using the ISIC 2018 dataset. The pre-processing phase is stringent as it insulates the cancerous fraction of a skin image, involving removing, trimming, thinning, and normalizing. In this phase, unwanted hair pieces on the image are eliminated in this phase. Feature extraction from the clipped image is achieved using a discrete cosine transform (DCT) and a gradient transform to transform it into frequency-domain coefficients. Statistical feature extraction is used to reduce the amount of data required for ANN training. A dataset from ISIC 2018 that consists of seven different images from dermoscopic procedures for classification purposes is used in the empirical investigation. An accuracy of 85.44% for DCT in the sub-bands and 76.07% for the sub-band gradient transform was achieved by the applied ANN. The hybrid system's mean squared error (MSE) was discovered to be 3.52×10-4. The work highlights the potential of ANN in the early detection of skin cancer, supporting more efficient treatment and preventing advanced cases.]]>
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