Background : Disturbance Wound healing is one of the complications of type 2 diabetes mellitus (DM). Disorders of leukocyte profile have been associated with DM pathogenesis and complications. Objective : To investigate the differential leukocyte count in patients with type 2 diabetes treated with diabetic vascular leg exercises. Methods : A re-experimental study design P with a one-group pre-test-post-test design was used in the study, which was conducted on people with DM in Bengkulu Tengah. Blood plasma specimen collection before (30 samples) and after (30 samples) diabetic vascular leg exercise. The leukocyte diffcount was analyzed microscopically. Results : There were significant differences in segmented neutrophils (p = 0.013), lymphocytes (p = 0.029), monocytes (0.043) in people with diabetes before and after diabetes exercise intervention. There was no significant difference in basophils (p = 1,000), eosinophils (p = 0.594), stem neutrophils (p = 0.236) in people with diabetes before and after the diabetes exercise intervention. Conclusion : diabetes physical exercise modulates leukocyte count differential in people with type 2 DM in Central Bengkulu. The results of the study support the development of diabetes physical exercise as a therapeutic modality for DM patients to prevent complications from a young age.
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