Neurona
Vol 38 No 1 (2020)

PENGARUH DERAJAT KEGANASAN TUMOR TERHADAP POLA GAMBARAN EEG PADA PENDERITA TUMOR OTAK PRIMER DI SUMATERA SELATAN

Wilasari Novantina (Departemen Neurologi Fakultas Kedokteran Universitas Sriwijaya/RSUP Dr. Mohammad Hoesin Palembang)
Yunni Diansari (Departemen Neurologi Fakultas Kedokteran Universitas Sriwijaya/RSUP Dr. Mohammad Hoesin Palembang)
Sri Handayani (Departemen Neurologi Fakultas Kedokteran Universitas Sriwijaya/RSUP Dr. Mohammad Hoesin Palembang)
Achmad Junaidi (Departemen Neurologi Fakultas Kedokteran Universitas Sriwijaya/RSUP Dr. Mohammad Hoesin Palembang)
Aspitriani Aspitriani (Departemen Patologi Anatomi Fakultas Kedokteran Universitas Sriwijaya/RSUP Dr. Mohammad Hoesin Palembang)
Irsan Saleh (Metodologi Penelitian Fakultas Kedokteran Universitas Sriwijaya.)



Article Info

Publish Date
01 Dec 2020

Abstract

Introduction: Brain tumor is one of the major malignancies with high morbidity and mortality. Treatment options and prognosis in patients with primary brain tumors based on the type and degree of malignancy. Definitive diagnosis and degree of malignancy in patients with primary brain tumors obtained from histopathological features. But unfortunately, histopathological features are not always available in all primary brain tumor sufferers. Electrenefalography (EEG) examination is a non-invasive examination that can record biological activity and neuron changes in brain cells. Brain tumor itself is an abnormal mass in the brain tissue that interferes with the electrical and biological activity of normal cells in the brain. Aim: To determine the association between the degree of malignancy of brain tumors and EEG patterns in patients with primary brain tumors in RSUP Dr. Mohammad Hoesin Palembang. Methods: This was a cross sectional study. The study sample was primary brain tumor patients who had undergone surgery and had EEG record and histopathological features.Data were analysed using SPSS 22. Results: The data obtained from 36 samples consist of 30 samples of low grade brain tumor patients, and 6 high grade brain tumor patients. There was a weak correlation between the degree of malignancy with focal slowing EEG pattern (r = 0.378; p = 0.014). There was no correlation between the degree of malignancy with epileptiform discharge (r = 0.177; p = 0.281), focal slowing accompanied by epileptiform discharge (r = 0.215; p = 0.187) ) and normal EEG (r = 0.110; p = 0.506). Discussion: The focal slowing EEG pattern has a correlation with the degree of malignancy. This is due to changes in peri-tumoral metabolism which is common in brain tumors Keywords: brain tumor, eeg pattern, degree of malignancy

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Journal Info

Abbrev

neurona

Publisher

Subject

Health Professions Medicine & Pharmacology Neuroscience

Description

Neurona merupakan satu-satunya jurnal yang memuat perkembangan penelitian dan kasus terbaru bidang neurosains oleh Perhimpunan Dokter Spesialis Saraf (PERDOSSI) Pusat di Indonesia. Jurnal ini diterbitkan bulan Maret, Juni, September dan Desember. Bidang studi cakupan NEURONA meliputi: Stroke dan ...