Prominentia Medical Journal
Vol 4 No 2 (2023): Prominentia Medical Journal

BIOMARKER PADA LUPUS NEFRITIS

Gisela Tania Irwanto (Dokter Umum Rumah Sakit Karanggede Sisma Medika Boyolali Jawa Tengah Indonesia)
Yuswanto Setyawan (Departemen Ilmu Penyakit Dalam Universitas Ciputra Surabaya Jawa Timur Indonesia)



Article Info

Publish Date
20 Nov 2023

Abstract

Lupus nephritis (LN) continues to be a leading cause of high morbidity and mortality rates in systemic lupus erythematosus (SLE) patients. Kidney biopsy remains the gold standard for diagnosing LN. Several biomarkers have been identified and evaluated, contributing to improvements in the management of LN patients. This literature review summarizes recent relevant literature on biomarkers for the diagnosis, monitoring, and prognosis of LN. These biomarkers are categorized based on their sample sources, namely serum and urine. Both sample sources show significant variations in biomarker data associated with disease activity and histological parameters of LN. Potential biomarker molecules include antibodies, cytokines, chemokines, and adhesion molecules. This literature review provides a general overview and serves as a reference for further research, particularly in advancing the understanding of LN biomarkers in Indonesia. Keywords: systemic lupus erythematosus (SLE), lupus nephritis (LN), biomarkers, serum, urin

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Journal Info

Abbrev

PMJ

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Focus and Scope PMJ (Prominentia Medical Journal) is a scientific journal focused on Medicine and Health. PMJ publishes Research Articles, Literature Reviews, and Case Reports that focus on Preventive Medicine and the Prevention of Lifestyle Diseases. Publication Frequency PMJ (Prominentia Medical ...