Al Makki Health Informatics Journal
Vol. 2 No. 1 (2024): Al Makki Health Informatics Journal

Anticancer Activity Of Guava Leaf Extract (Psidium Guajava)

Tarizza Puspa Anggrelia Tarizza Puspa Anggrelia (Universitas Anwar Medika)
Icasia Carolina Dewi Icasia Carolina Dewi (Universitas Anwar Medika)
Ria Lestari Herawati Ria Lestari Herawati (Universitas Anwar Medika)
Sovia Maulina Azkiyah Sovia Maulina Azkiyah (Universitas Anwar Medika)
Ana Fatmah Az Zahro Ana Fatmah Az Zahro (Universitas Anwar Medika)
Ramadhan Putra Maulana Ramadhan Putra Maulana (Universitas Anwar Medika)
Agustinus Alfred Seran Agustinus Alfred Seran (Universitas Anwar Medika)
Ivan Charles S.Klau Ivan Charles S.Klau (Universitas Anwar Medika)
Arista Wahyu Ningsih Arista Wahyu Ningsih (Universitas Anwar Medika)



Article Info

Publish Date
06 Feb 2024

Abstract

Free radicals are chemical compounds that are highly reactive and have the possibility of being detrimental to the body's cells. At high levels, free radicals can pose a serious risk to health, inflicting damage to major components of cells. Cell damage caused by free radicals, especially to Deoxyribonucleic Acid (DNA), can result in the development of cancer and other health problems. Guava seed leaves (Psidium guajava) are the focus of research because of their potential in reducing the growth of breast cancer cells. The study details the results of two literature review studies that support this claim. The bioactive compounds such as polyphenols, flavonoids, phenolic acids, and ascorbic acid found in guava seeds have been linked to antioxidant and anti-inflammatory properties. The first study by showed that guava leaf extract has anti-proliferative activity against breast cancer cells (MDA-MB-231 and MG-63). The second study highlighted the cytotoxic activity of 70% ethanol extract from guava leaves against T47D breast cancer cells. The results of both studies showed that guava seeds have the potential to inhibit the growth of breast cancer cells, indicating a possible role for guava seeds in breast cancer prevention strategies.

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Journal Info

Abbrev

hij

Publisher

Subject

Dentistry Health Professions Nursing Public Health Veterinary

Description

l Makki Health Informatics Journal is an open-access scientific peer-review journal publishing. The Al Makki Health Informatics Journal focuses on exchanging information relating to intelligent computing and health informatics applied in industry, hospitals, government, and universities. All ...