The Indonesian Journal of Public Health
Vol. 18 No. 3 (2023): THE INDONESIAN JOURNAL OF PUBLIC HEALTH

A COMPARATIVE OBSERVATIONAL STUDY ON EFFECTIVENESS OF PROBIOTICS AND ANTIBIOTICS IN BACTERIAL VAGINOSIS

Sowmya B (Department of OBG, IMS & SUM Hospital, Siksha O Anusandhan (Deemed to be University), Bhubaneswar-751003, Odisha, India)
Dattatreya Kar (Department of Medical Research, IMS & SUM Hospital, Siksha O Anusandhan (Deemed to be University), Bhubaneswar-751003, Odisha, India.)
Rajashree Panigrahy (Department of Microbiology, IMS & SUM Hospital, Siksha O Anusandhan (Deemed to be University), Bhubaneswar-751003, Odisha, India.)
Basanta Pati (Department of OBG, IMS & SUM Hospital, Siksha O Anusandhan (Deemed to be University), Bhubaneswar-751003, Odisha, India.)



Article Info

Publish Date
16 Nov 2023

Abstract

Introduction: Bacterial vaginosis is a common vaginal dysbiosis in women of reproductive age. Bacterial vaginosis is a dysbiosis characterized by a reduction of Lactobacillus species, such as L. crispatus, L. gasseri, and L. Jensenii. Anti-microbial resistance of BV pathogens and low long-term cure rates have been increasing in the few years. Aim: Probiotics are proposed as an alternative treatment for BV applying live micro-organisms with the capacity to confer health benefits to the patient. Methods: Patients with white discharge per vagina with or without foul smell, and itching visiting Obstetrics and Gynecology OPD are subjected to Amsel criteria. Those test positive for 3 out of 4 are diagnosed to have bacterial vaginosis and were enrolled in the study. Result: Highest prevalence of bacterial vaginosis was at the age group of 26-30 years (28%), with the lowest prevalence (16%) above 40 years of age. Among group A (probiotics),  68% and 32% of women were in not working and working groups, respectively, when compared with group B (antibiotics), 64% and 36% of women were in not working and working groups. Nulligravida (28% and 32%), Singleton Pregnancy (32% and 16%) in Group A and Group B. We observed that patients treated with both antibiotics (50%) and probiotics (50%) had similar recurrence rates of BV. Conclusion: Hence it would be prudent to prefer probiotics in patients with BV, as they colonize other normal commensals and have similar efficacy as that of antibiotics. The other beneficial factors of probiotics include acceptability to patients and nil side effect profile.

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Journal Info

Abbrev

IJPH

Publisher

Subject

Public Health

Description

The Indonesian Journal of Public Health published since 2004, is a scientific journal article presents the results of research and review of the literature on the development of science that includes the study of Public Health Epidemiology, Administration & Policy Health, Health Promotion and ...