Jurnal Ilmiah Kedokteran Wijaya Kusuma
Vol 13, No 1 (2024): March 2024

Role of Anemia and Leukocytosis as Severity Predictors of Coronary Artery Disease Stenosis : A Retrospective Cross-sectional Study

M Saugi Abduh (Internal Medicine Department, Faculty of Medicine Sultan Agung Islamic University – Sultan Agung Islamic Teaching Hospital, Semarang Indonesia)
Muhammad Rizki Triono (Research Assistant, Division of Respirology and Critical Illness, Department of Internal Medicine Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital, Jakarta, Indonesia)
Retno Widyastuti (Internal Medicine Department, Faculty of Medicine Sultan Agung Islamic University – Sultan Agung Islamic Teaching Hospital, Semarang Indonesia)



Article Info

Publish Date
29 Mar 2024

Abstract

Background: Anemia and leukocytosis were found to be associated with conditions that higher the risk for the formation of atherosclerotic plaque which will develop into cardiovascular disease. Basic laboratory parameters such as anemia and leukocytosis are not routinely used to assess Coronary Artery Disease (CAD) severity based on its stenosis. This study aimed to analyze the role of simple laboratory examiantion anemia and leukocytosis as predictors of the severity of stenosis in CAD. Methods: Cross-sectional approach was used in this study. Secondary data on CAD patients treated at Sultan Agung Islamic Hospital Semarang in 2022 were analyzed. Anemia and leukocytosis are the main risk factors analyzed in this study. Other risk factors such as gender, age, smoking status, hypertension and diabetes mellitus (DM) were also included in the analysis of this study. We performed bivariate analysis and multivariate analysis to see the relationship between these risk factors and the CAD stenosis severity. Results: Bivariate analysis with chi-square showed that anemia had a significant relationship with CAD severity (P<0.05). Multivariate analysis between anemia and smoking status reported that anemia was the most significant risk factor for the CAD stenosis severity (P<0.05). Conclusion: No association found between leukocytosis and CAD severity.

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Journal Info

Abbrev

JIKW

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published ...