Jurnal Medika Veterinaria
Vol 15, No 1 (2021): J.Med.Vet

10. Potency of Clove Leaf Ethanol Extract (Syzygium aromaticum L) Against Differentiation of Leukocytes in White Rats (Rattus norvegicus) Experiencing Incision Wounds

Charles Eko Masihin (Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura)
M Kaihena (Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura)
A J A Unitly (Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura)



Article Info

Publish Date
25 Jan 2022

Abstract

This study aims to determine the difference in leukocytes of white rats (Rattus norvegicus) that suffered from incision wounds after being treated with clove leaf ethanol extract (Syzygium aromaticum L). The study used 15 white rats divided into five groups, and each was replicated three times. P1 is a negative control group, namely, rats with incisions made without medication. P2 is a positive control; namely, rats made incisions and were given betadine. P3 is a group of rats with incisions made and given clove leaf ethanol extract at a dose of 0.09 g/head/day for 14 days. P4 is a group of rats with incisions made and given clove leaf ethanol extract at a dose of 0.18 g/head/day for 14 days. P5 is a group of rats with incisions made and given clove leaf ethanol extract at a dose of 0.36 g/head/day for 14 days. After 14 days, the rats were dissected, and their blood was taken for analysis using a hematology analyzer to determine the difference in leukocytes. The results showed that there was a significant difference when presenting the ethanol extract of clove leaves (P0.05). It was concluded that presenting the ethanolic extract of clove leaf increased the differentiation of rats with incisional wounds.

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Journal Info

Abbrev

JMV

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

Description

Jurnal Medika Veterinaria is published biannually in February and August. The scope of this journal includes Veterinary Medicine, Animal Science, Science, and Medicine. The journal accepts original research papers, case study, and review article. All submissions are evaluated by peer reviewers who ...