The prevalence of leftover medicines that are still stored in households is still quite high, including people still storing medicines that have expired. Children are a vulnerable age group who often receive compounded and non-compounded medicines. The purpose of this study was to compare the attitudes of the two groups of mothers towards leftover compounded drugs and non-compunded drugs with assessment aspects namely storage of leftover drugs, reuse, and re-examination. This research is a quantitative-analytical research, non-experimental, with a cross-sectional design used in this study. Data was obtained from mothers of children who received treatment, carried out by guided interviews using an interview instrument containing 8 statements. The data was then processed statistically using the Chi Square test. The results showed that the age of most respondents was in the range of 26-35 years, the most recent education being high school, and as housewives, and using insurance. The percentage of respondents who showed a positive attitude on the aspects of remaining drug storage, reuse, re-examination in the compunded group (97.5%; 95%; 98.8%) showed a higher percentage than the non-compounded group (86.2%; 85% ; 97.5%). Both groups showed significant differences in aspects of leftover drug storage and reuse.
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