Medical Sains : Jurnal Ilmiah Kefarmasian
Vol 9 No 1 (2024)

LIQUID SOAP FORMULATION FROM ETHANOLIC EXTRACT OF CASSAVA LEAVES (Manihot esculenta Crantz) WITH COCAMIDE DEA AS SURFACTANT

Nooryza Martihandini (Politeknik Kesehatan Kementerian Kesehatan Tasikmalaya)
Diani Putria Angelica (Politeknik Kesehatan Kementerian Kesehatan Tasikmalaya)
Shandra Isasi Sutiswa (Politeknik Kesehatan Kementerian Kesehatan Tasikmalaya)



Article Info

Publish Date
21 Feb 2024

Abstract

The ethanol extract of cassava leaves contains various secondary metabolites that have antibacterial activity against Escherichia coli, Staphylococcus aureus, and Shigella sp., and thus can be used as active ingredients in liquid soap preparation. Liquid soap formulations generally use sodium lauryl sulfate (SLS) as a surfactant, which can cause irritation and skin dryness. This study aimed to formulate an ethanol extract from cassava leaves into a liquid soap preparation using cocamide DEA as a surfactant to reduce skin irritation. The study was conducted in an experimental laboratory. Cassava leaves were extracted by maceration using ethanol. Three liquid soap formulas from cassava leaf extract were developed with different extract concentrations: F1 (1%), F2 (3%), and F3 (5%). The liquid soaps were evaluated in terms of organoleptic properties, pH, homogeneity, viscosity, foam height, and foam stability. The study showed that cassava leaves extract could be formulated into a homogeneous liquid soap with a pH range of 7.0–7.5, viscosity of 143.6–306.2 cps, foam height of 53.33–60.00 mm, and foam stability of 75.01–82.36%. F3 is the optimum formula with the best physical characteristics of the preparation in terms of organoleptic properties, foam height, and foam stability. Keywords: cocamide DEA, cassava leaves, liquid soap, surfactant

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Journal Info

Abbrev

iojs

Publisher

Subject

Medicine & Pharmacology

Description

The Medical Sains journal is a scientific publication media published by the Muhammadiyah Cirebon College of Pharmacy which is published 4 (four) times in 1 (one) year, namely January-March, April-June, July-September and October-December. The journal contains research in the field of pharmacy ...