<![CDATA[Background: Diffusion Weighted Imaging (DWI) is a technique that visualizes the movement of water molecules from areas of higher to lower concentration. In DWI sequences, the b-value parameter affects the signal intensity in the images. The objective of this study is to describe the differences in anatomical image information between b-value variations of 1500s/mm2, 2000s/mm2, and 2500s/mm2 in MRI prostate case cancer and to determine the most optimal b-value. Method: This study used a pre-exeachimental approach with a 1.5T Philips MRI machine at a private hospital in South Jakarta from March to April 2023. The sample consisted of 12 Prostate MRI images with DWI sequences and different b-values. Visual grading assessment was eachformed by three radiology specialists, and the data were analyzed using the Friedman test in SPSS. Results: The results showed a significant difference in anatomical image information based on the b-value variations used, with a p-value of 0.05 (0.02). The highest mean rank was obtained from the Friedman test for the b-value of 2000s/mm2. Conclusion: The significant difference in anatomical image information occurred due to differences in signal intensity and noise levels. Prostate cancer tissues appeared more hyperintense with lower noise in images with higher b-values, and vice versa. Additionally, the b-value of 2000s/mm2 resulted in the most optimal signal intensity and noise level. In conclusion, the use of b-value variations in axial DWI images of prostate cancer Prostate MRI to differences in anatomical image information, with the most optimal image information observed at a b-value of 2000s/mm2.]]>
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