Potensi Ekstrak Etanol Kulit Batang Jabon (Anthocephalus cadamba (Roxb) Miq.) Sebagai Antiinflamasi

Nur F. Bakri (Universitas Cenderawasih)
Rusnaeni (Universitas Cenderawasih)
Sarce M. Sasarari (Universitas Cenderawasih)
Elsye Gunawan (Universitas Cenderawasih)

JURNAL BIOLOGI PAPUA
Vol 16 No 1 (2024)

This study investigates the anti-inflammatory properties of an ethanol extract from Jabon plant stem bark in male mice using the Rat Hind Paw Edema method. Twenty-five male mice were divided into five groups: negative control (Na-CMC 1%), positive control (mefenamic acid), and three groups receiving the extract at doses of 50 mg/kg, 100 mg/kg, and 200 mg/kg. Measurements were taken every 30 minutes for three hours using a plethysmometer. Analysis with one-way ANOVA and Duncan's test revealed significant anti-inflammatory effects for all doses, with the most effective being 100 mg/kg, showing 93.42% inhibition. The results suggest Jabon plant extract as a promising anti-inflammatory agent.