Acta Pharmaciae Indonesia : Acta Pharm Indo
Vol 11 No 1 (2023): Acta Pharmaciae Indonesia : Acta Pharm Indo

Escherichia coli dominance and antimicrobial resistance in urinary tract infections among diabetic patients: Insights from Birnin Kebbi Metropolis, Nigeria

Almustapha, Adamu Aliero (Unknown)
Yari, Haruna Abdullahi (Unknown)
Ibrahim, Ahmad Bagudo (Unknown)
Manga, Sule Sahabi (Unknown)
Tomo, Farida Abubakar (Unknown)
Muhammad, Amina (Unknown)
Muhammad, Muhammad Shamsudeen (Unknown)



Article Info

Publish Date
29 Nov 2023

Abstract

Background: The global rise in antibiotic-resistant urinary tract infections (UTIs) is a growing concern, particularly among diabetic patients. This study examines the antibiotic resistance patterns of bacterial uropathogens in diabetic patients at Sir Yahaya Memorial Hospital in Birnin Kebbi. Methods: A purposive sampling approach was used to collect 51 mid-stream urine samples in sterile containers. Cultural and biochemical methods were employed for the isolation and identification of uropathogenic bacteria. Antibiotic sensitivity testing was performed using the disc diffusion method, with results interpreted according to the Clinical Laboratory Standards Institute (CLSI) guidelines. Results: UTIs were prevalent in 23.5% (12/51) of the samples. Escherichia coli was the most prevalent uropathogen, accounting for 41.3% (7/17) of cases, followed by Klebsiella pneumoniae at 23.5% (4/17). Staphylococcus aureus and Proteus mirabilis each contributed to 17.6% (3/17) of cases. Notably, E. coli and K. pneumoniae exhibited 100% resistance to chloramphenicol and sparfloxacin, respectively. Conclusion: These findings underscore the need for further molecular research to characterize these uropathogens and identify the genes contributing to antibiotic resistance.

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Journal Info

Abbrev

api

Publisher

Subject

Medicine & Pharmacology

Description

Journal of Acta Pharmaciae Indonesia is a journal published twice a year by Pharmacy Department, Jenderal Soedirman University, Purwokerto with the Number of ISSN 2337-8433 and E-ISSN 2621-4520. Our journal discusses various pharmaceutical fields in terms of Pharmaceutics & Pharmaceutical ...