<![CDATA[This research was conducted to determine the substrate composition, inoculum dose and fermentation time that are suitable for the growth of Pleurotus ostreatus on a substrate mixed with cocoa pod skin (KBK) with tofu dregs, soy milk dregs and bran on crude fiber content and crude fiber digestibility. This research used an experimental method with a 3x3x3 Factorial Completely Randomized Design (CRD) with 2 replications. Factor A is a substrate composition with a ratio of 80% cocoa pod skin and 20% each for tofu dregs, soy milk dregs and bran. Factor B is the inoculum dose, namely 6%, 8% and 10%, and factor C is the fermentation time, namely 7, 9 and 11 days. The results of the analysis showed that there was an interaction between substrate composition and fermentation time with Pleurotus ostreatus which had a significantly different effect (P<0.05) on crude fiber content and crude fiber digestibility. The conclusion of this study was that the selected treatment was in the A1B3C2 treatment (80% cocoa pod skin and 20% tofu dregs at a dose of 10% with a fermentation time of 9 days) reducing crude fiber by 48.14% and crude fiber digestibility by 57.86%. .]]>
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