UJI AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS EKSTRAK N- HEKSAN DAN ETIL ASETAT RANTING SIRIH HUTAN (Piper aduncum L.)

Yerwanto Ilang (Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman)
Syelvia Lousiana Kalauw (Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman)
Rudi Kartika (Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman)
Fauzi Rachman (aboratorium Kimia Bahan Alam, Puslit Bioteknologi Lembaga Ilmu Pengetahuan Indonesia (LIPI))

PROSIDING SEMINAR KIMIA
SEMINAR NASIONAL KIMIA 2014

The aim of this study was to determine the antio xidant and toxicity act ivities of n-hexane and ethyl acetate of Piper aduncum L. (family : Piperaceae). Antio xidant activities of the ext racts was assessed by means of DPPH free radical scavenging method used ascorbic acid as standard with IC 50 value was 4,841 μg/mL. Piper aduncum L. showed n-hexane extract demonstrated the good antioxidant activity with IC 50 value of 40,034 μg/ mL and the ethyl acetate extract is 59,838 μg/ mL. The Brine shrimp letality bioassay met od as sed to determine t e cytotoxicity activities. The LC 50 values of n-hexane and ethyl acetate extracts were 25,12 and 17,78 μg/ mL, respectively.