This study aims to determine the effectiveness of areca nut ethanol extract cream on healing incision wounds in rabbits. This study is an experimental study in the Laboratory using 1%, 2%, and 3% areca nut extract cream as test samples and betadine cream as a positive control and cream base as a negative control tested on rabbits. The results of this study obtained a wound healing effect on betel nut extract cream 1% by (4,25%) per day, betel nut extract cream 2% by (6,00%) per day, and betel nut extract cream 3% by (6.75%) per day.
                        
                        
                        
                        
                            
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