Jurnal Penelitian Farmasi dan Herbal
Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal

TESTING FOR ANTIBACTERIAL ACTIVITY OF FRUIT SKIN ETHANOL EXTRACT DUKU (Lansium domesticum Corr) AGAINST BACTERIA Salmonella Typhi

Wulandari, Suci (Unknown)



Article Info

Publish Date
05 May 2024

Abstract

Salmonella typhimurium bacteria is the cause of typhoid fever. One of the herbal plants that can be used as an antibacterial drug is duku fruit peel (Lansium domesticum Corr). Phytochemical tests were carried out on duku fruit peel extract which was soaked in 96% ethanol solvent. The aim of this test is to identify secondary metabolites found in duku fruit skin. There are alkaloids, flavonoids, saponins, tannins and triterpenoids in the ethanol extract of duku fruit peel. This study involved four treatment groups with extract concentrations of 25 percent, 50 percent, and 75 percent, along with a positive control (chloramphenicol) and a negative control (distilled water). With inhibition zone diameters of 10.22 mm, 11.94 mm, and 13 mm, the ethanol extract of duku fruit peel showed antibacterial activity against Salmonella enterica bacteria. The results of univariate data analysis showed that the ethanol extract of duku fruit peel showed antibacterial activity at 25%, 50% and 75%. The results of univariate data analysis showed that the ethanol extract of duku fruit peel showed antibacterial activity against Salmonella typhi bacteria. In addition, the bacterial concentration increases with the width of the inhibition zone.

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Journal Info

Abbrev

JPFH

Publisher

Subject

Medicine & Pharmacology

Description

Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is ...