Journal of Global Pharma Technology
Volume 16 Issue 03 (2024) March 2024

EXPLORING POST-COMPRESSION PARAMETERS IN MARKETED VILDAGLIPTIN TABLETS

Siva, P Krishna (Unknown)



Article Info

Publish Date
15 Feb 2024

Abstract

This study investigates the post-compression parameters of tablets produced by five prominent pharmaceutical brands. Tablets play a crucial role in drug delivery, and their quality is essential for ensuring therapeutic efficacy. The post-compression phase is a critical step in tablet manufacturing, influencing key parameters such as weight variation, hardness, friability, and disintegration. This research aims to assess and compare these parameters for tablets from five selected brands, confirming their adherence to quality standards. The tablets from Brand A, Brand B, Brand C, Brand D, and Brand E underwent a rigorous testing protocol to evaluate hardness using a calibrated hardness tester, friability through Roche friabilator, and disintegration employing a disintegration tester. The study utilized standardized testing methods to ensure consistency and reliability across all assessments. Results revealed that all five brands successfully met benchmarks for weight variation, hardness, friability, and disintegration time. The tablets demonstrated robust mechanical strength, minimal friability, and prompt disintegration of active pharmaceutical ingredients. Keywords: Post-compression, Hardness, Friability, Disintegration.

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Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...