The problem of drug misuse among teenagers considered a national issue and becomes the concern quite hard to deal with. Teenagers are at risk for drug usage as this period is a phase of transition between childhood and adulthood known as a searching or self-identity period. This study aims to know the underlying factors to prevent drug use among teenagers at MAN 6 Kuta Baro, Aceh Besar. This research method used analytical design with a cross sectional approach with population of 118 adolescents and total sample of 54 teenagers. The proportional random sampling was used for data collection technique. This research was conducted on March 10, 2023 with univariate and bivariate analysis using the chi square test. The findings indicated that out of 54 respondents, 29 people (53.7%) made fewer attempts to prevent drug use, 32 people (59.3%) had less awareness of the dangers of using drugs, 35 people (64.8%) had negative atititude towards drugs, and less involvement from peers as many as 34 people (63%). These findings indicates that there is a relation between knowledge (p=0.003), attitudes (p=0.007), and the role of peers (p=0.017) with drug prevention attempts. In conclusion, the prevention of drug use is affected by knowledge, attitude, information, and the involvement of peers. It expects the research area to provide health counseling regarding drugs and collaborate with cross-sectoral organizations - The Health Offices and Public Health Centers.
                        
                        
                        
                        
                            
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