Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy)
No 1 (2024): JIFFK Special Edition Suppl. 2

Kandungan Metilparaben Dan Propilparaben Dalam Krim Wajah Yang Beredar Di Wilayah Labuan Kabupaten Pandeglang

Neng Nurul Fitri (Universitas Muhammadiyah A. R Fachruddin)
Nita Rusdiana (Universitas Muhammadiyah A. R Fachruddin)
La Ode Akbar Rasydy (Universitas Muhammadiyah A. R Fachruddin)



Article Info

Publish Date
20 Aug 2024

Abstract

Methylparaben and propylparaben are compounds that can be used as antibacterials in cosmetics, one of which is in cream preparations. However, if parabens are used excessively, they can cause side effects in the form of increased estrogen, weight gain, irritation, decreased reproductive health, and premature aging. This study aims to identify and determine the levels of methylparaben and propylparaben contained in face creams circulating in the Labuan Region, Pandeglang Regency using the High Performance Liquid Chromatography method. The mobile phase used was methanol: water (4:6), temperature 25oC, flow rate 1.2 mL/min, wavelength 257 nm using an octadecylsilane (C18) column. The results of the four face cream samples used, the samples with the KW 1 and KW 2 codes were not identified as using the preservative methylparaben, the samples with the KW 3 and KW 4 codes contained methylparaben with levels that were still below the maximum limit set by BPOM, namely 0.4% for single preservative use and 0.8% for mixed preservative use. The average percentage of methylparaben content in KW 3 and KW 4 was 0.21% and 0.20%. Meanwhile, the preservative propylparaben was not identified in samples with the codes KW 1, KW 2, KW 3 and KW 4.

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Journal Info

Abbrev

Farmasi

Publisher

Subject

Medicine & Pharmacology

Description

Selamat datang di situs e-Publikasi Ilmiah Fakultas Farmasi Unwahas (Universitas Wahid Hasyim) Semarang. Situs ini berisi kumpulan publikasi ilmiah yang diterbitkan oleh Fakultas Farmasi Unwahas. Publikasi berasal dari jurnal-jurnal serta hasil prosiding seminar yang dilaksanakan oleh Fakultas ...