This research aims to determine the extent of influence, liquidity and leverage on the profitability of pharmaceutical sector manufacturing companies listed on the Indonesia Stock Exchange for the 2019-2022 period. This research is quantitative research. The population of this research is all pharmaceutical sector manufacturing companies listed on the Indonesia Stock Exchange for the 2019-2022 period. Sample selection was carried out using the purposive sampling method and resulted in a selected sample of 35 samples. The data collection technique used is documentation, with documents in the form of company financial reports for 2019-2022. The data analysis technique uses descriptive analysis, classical assumption testing, and hypothesis testing using multiple linear regression analysis with SPSS 16 tools. The results of the research show that: both variables have a significant effect on Y. and an Adjusted R Square value of 0.363 or 36.3 is obtained. % This means that 36.3% of the profitability variable is influenced by liquidity and the remaining 63.7% of leverage is influenced by other variables outside of this research variable.
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