The Journal of Pure and Applied Chemistry Research
Vol. 13 No. 1 (2024): Edition January-April 2024

Phytochemical screening, investigation of the antisalmonella, antishigella, and antioxidant properties of the leaves of Rauvolfia vomitoria Afzel

Kpadonou-Kpoviessi, Bénédicta (Unknown)
Noudamadjo, Amandine (Unknown)
Goueti, Basile (Unknown)
Atchade, Bardieu (Unknown)
Djouonzo Toukam, Paul (Unknown)
Gbenou, Joachim (Unknown)
Glinma, Bienvenu (Unknown)
Dossou Sika KPOVIESSI, Salomé (Unknown)



Article Info

Publish Date
06 May 2024

Abstract

Rauvolfia vomitoria is a plant acclimatized in Benin - Africa that people use to treat several illnesses such as malaria, cough, typhoid fever, madness, toothache, diabetes, and nausea. The most used organs are leaves, stems, and roots. Thus, the purpose of this work is to contribute to the valorization of R. vomitoria by chemical and biological studies of this plant. Phytochemical analyses of the powder extracts were performed and revealed the presence of alkaloids, tannins, flavonoids, anthocyanins, saponins, terpenes, coumarins, mucilages, reducing compounds, free anthracene derivatives, bound anthracene derivatives (O-glycosides and C-glycosides) with absence of leuco-anthocyanins, quinone derivatives, steroids and cardiotonic glycosids. Evaluation of antisalmonella and antishigella properties of ethanol-water (70:30; V/V) and ethanolic extracts of R. vomitoria leaves showed minimum inhibitory concentrations (MIC) greater than 2000 µg.mL-1 against Salmonella and Shigella strains. The ethanolic extract was the most active by ABTS and FRAP methods and had very good antioxidant activity at scavenging concentration (SC50) equal to 138,62 µg.mL-1 and 185,99 µg.mL-1 respectively

Copyrights © 2024






Journal Info

Abbrev

jpacr

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry Materials Science & Nanotechnology Medicine & Pharmacology

Description

The Journal of Pure and Applied Chemistry Research focuses in publishing research articles in the field of Chemistry and Applied Chemistry. The target is in exploring, investigating, and developing chemicals sources from local and/or Indonesian to increase the value. Scope of the journal is organic ...