Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan

Modification of Gemifloxacin Drug Antibacterial to Promising Anti-Prostate Cancer PC3 Azomethine Compounds: Synthesis and in Vitro Studies

Rand Thair Abdulkader (Unknown)
Reyam H. Marah (Unknown)
Aqeel Mohamed (Unknown)
Abbas K. Abbas (Unknown)

Article Info

Publish Date
15 Aug 2024

Abstract

In this study, we report a novel azomethine derivatives synthesis (H and G) by reacting pure Gemifloxacin drugs with 2-aminobenzaldehyde and 2-methylbenzaldehyde. Spectroscopic techniques, such as FT‐IR spectroscopy, characterized the derivatives (G and H). All the synthesized derivatives (G and H) were evaluated in vitro against microorganisms such as Bacillus subtilis and E. coli by zone inhibition method and screened for antimicrobial activities and anti-Prostate cancer PC3 cell viability cell lines.

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Journal Info
Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Website

Abbrev

OBAT

Publisher

Asosiasi Riset Ilmu Kesehatan Indonesia

Subject

Health Professions Nursing Public Health

Description

Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan ...