Prominentia Medical Journal
Vol 5 No 1 (2024): Prominentia Medical Journal

VITAMIN D PADA ASMA BRONKIAL

Setyawan, Yuswanto (Unknown)



Article Info

Publish Date
29 May 2024

Abstract

Bronchial asthma is a lung disease characterized by reversible airway obstruction both spontaneously and with treatment, characterized by airways inflammation and hyperreactivity to various stimuli. Until now, the most effective treatment for asthma are corticosteroids and β-agonists, while the administration of prophylactic drugs is often less effective and often causes very disturbing side effects. Vitamin D is a group of fat-soluble secosteroids. Vitamin D has functions in modulating neuromuscular function, reducing inflammation and influencing the work of various genes that regulate cell proliferation, differentiation and apoptosis. Research shows that low levels of vitamin D are associated with increased allergy markers and asthma levels. Vitamin D is believed to play a role in asthma by inhibiting respiratory tract smooth muscle proliferation via hyperphosphorylation of the retinoblastoma protein and activation of checkpoint kinase 1 (Chk1). Vitamin D has recently been considered as a treatment for asthma.

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Journal Info

Abbrev

PMJ

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Focus and Scope PMJ (Prominentia Medical Journal) is a scientific journal focused on Medicine and Health. PMJ publishes Research Articles, Literature Reviews, and Case Reports that focus on Preventive Medicine and the Prevention of Lifestyle Diseases. Publication Frequency PMJ (Prominentia Medical ...