Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics)
VOLUME 12 ISSUE 4, 2024

Potential of avocado oil (Persea americana) in improving triglyceride and High Density Lipoprotein (HDL) levels in rats (Rattus novergicus) model of dyslipidaemia due to high fat diet

Sari, Eka Puspita (Universitas Sebelas Maret Surakarta)
Wasita, Brian (Sebelas Maret University of Surakarta)
Muthmainah, Muthmainah (Sebelas Maret University of Surakarta)



Article Info

Publish Date
13 Sep 2024

Abstract

Background: Elevated levels of Dyslipidaemia pose a significant threat to cardiovascular health. Fortunately, the abundance of polyunsaturated and monounsaturated fatty acids (PUFA and MUFA) present in avocado oil offers a promising avenue for individuals with Dyslipidaemia to improve their lipid profile levels.Objectives: The objective of this research is to ascertain the potential of avocado oil in improving triglyceride and HDL levels.Methods: A pre-post test control group design was employed, utilizing male Wistar rats aged 8 weeks with a body weight ranging from 150-200 g. The mice were segregated into six groups: N, K-, K+, P1, P2, and P3. Throughout the trial, solely group N abstained from ingesting avocado oil or HC. Conversely, all other groups were administered HC and subsequently, K+ was prescribed simvastatin while P1, P2 and P3 received avocado oil for a duration of 28 days. The data was subjected to statistical analysis using SPSS vr.25. The statistical significance threshold was set at p<0.05.Results: Mean changes in levels (mg/dL) for TG -29.67 (P1), -48.99 (P2), -56.78 (P3) and for HDL 41.75 (P1), 46.35 (P2). There was a significant difference in TG and HDL levels between P1, P2, P3 when compared with K- (p<0.05).Conclusion: Avocado oil exhibits efficacy in lowering TG levels and elevating HDL levels, rendering it a viable option for daily consumption.

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Journal Info

Abbrev

IJND

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health Other

Description

Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) abbreviated IJND (p-ISSN 2303-3045 and e-ISSN 2503-183X) is a peer-reviewed scientific journal publishing updated research and non-research articles in the area of nutrition and dietetics. This journal is published ...