<![CDATA[The research aimed to assess the Biotechnology Encyclopedia's suitability as a learning resource for Biotechnology students, involving material, design, and learning experts. Developed using the ADDIE model, the study included sixth-semester students from the Biology Education Program at Medan State University. Sampling involved 56 students selected through simple random sampling. Data collection utilized questionnaires, tests, and interviews, analyzed quantitatively and qualitatively. Material and design experts rated the encyclopedia positively but suggested minor revisions, with 72% and 86% respectively in the "good" and "very good" categories. Similarly, learning experts and lecturer responses were in the "very good" category at 94% and 85% respectively. Student responses were overwhelmingly positive, with 87% in the "very good" category without revisions. T-test results showed a significant difference in scientific literacy abilities between the experimental and control classes (9.344 > 2.002), indicating the effective impact of the Biotechnology Encyclopedia based on scientific literacy.]]>
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