Infancy is the period after birth before 59 months of age. Death in infants can be caused by several things, and one of the biggest causes of death in infants is due to infection. increased risk of therapeutic failure, one of the impacts that need to be aware of is the potential for resistance when the antibiotics given cannot reach the minimum level to inhibit growth or kill bacteria. The occurrence of problems in NICU patients due to antibiotic use caused by antibiotic use. This research method is by collecting data obtained from medical records and families of patients treated at Sembiring Delitua General Hospital by observing the use of antibiotics for 28 days. The results obtained were several antibiotics, namely Cefotaxime, Gentamicin, Cefadroxil, Ampicillin, and Meropenem. The conclusion of this study is that the type of antibiotic used is cefotaxime, the results of the analysis of antibiotic suitability in patients who receive a diagnosis of infection are in accordance with the needs of the patient and have fulfilled the 4T1W criteria (right drug, right patient, right indication and alert side effects).
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