Modification, Characterization, and Catalytic Application of Mesolite for One Pot Synthesis of 3-Methyl-4-arylmethylene-isoxazol-5(4H)-ones

Ganesh Trambakrao Pawar (Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431004)
Sachin Pandit Gadekar (Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431004)
Balasaheb R. Arbad (Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431004)
Machhindra Karbhari Lande (Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431004)

Bulletin of Chemical Reaction Engineering & Catalysis
2017: BCREC Volume 12 Issue 1 Year 2017 (April 2017)

Natural mesolite type zeolite was collected, modified by sulphuric acid treatment and characterized by using Powder-X ray diffraction, Scanning electron microscopy and Energy dispersive spectroscopy, Fourier transform infrared spectroscopy. Temperature programmed ammonia desorption, Brunauer-Emmer-Teller surface area analysis. Modified dealuminated mesolite shows an efficient catalytic activity for one pot synthesis of 3-methyl-4-arylmethylene-isoxazol-5(4H)-ones derivatives, via one pot three component condensation of benzaldehyde, ethylacetoacetate and hydroxylamine hydrochloride. Present method offers several advantages over the reported methods like a simple and inexpensive modification of catalyst, mild reaction condition, easy separation of catalyst, simple work-up procedure, nonchromatographic isolation and purification desired product and excellent yield. Furthermore, catalyst could be reused without significant loose in activity.