<![CDATA[Background: Long working hours are known to have a negative impact on health. This study aims to explore the association between long working hours on depression and mental well-being with a nationally representative sample. Subjects and Method: A cross-sectional study was conducted on 176 resident doctors and young doctors in Indonesia via Google Forms from November 2022 to July 2023. Depression and mental well-being were evaluated using the Patient Health Questionnaire-9 (PHQ-9) and the World Health Organization's five-item Well-Being Index (WHO-5). The correlation between working hours (< 12 hours and ≥ 12 hours on weekdays) and depression was analyzed using multiple linear regression, while the interrelation between working hours and mental well-being applied multiple logistic regression. Results: A total of 53 (30.11%) resident doctors and junior doctors worked ≥ 12 hours on weekdays. Multiple linear regression analysis revealed that individuals with work duration ≥ 12 hours had a probability of experiencing depression 1.93 units higher than those who worked < 12 hours (b= 1.93; 95% CI= 0.35 to 3.51; p= 0.017). The multiple logistic regression model shows that individuals with work periods of ≥ 12 hours are 2.69 times more at risk of having poor mental well-being than those who work < 12 hours (OR= 2.69; 95% CI= 1.26 to 5.74; p= 0.010). Conclusion: Working too long is significantly associated with the development of depressive symptoms and poor mental well-being. Management of working hours for resident doctors and young doctors is essential for maintaining physical and psychological health in order to improve the quality of care. Keywords: long working hours, depression, mental well-being]]>
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