Interdental Jurnal Kedokteran Gigi (IJKG)
Vol. 20 No. 3 (2024): Interdental Jurnal Kedokteran Gigi (IJKG)

The Corticosteroids Intralesional Injections as a Treatment of Oral Lichen Planus: Systematic Literature Review

I Nyoman Gede Juwita Putra (Department of Oral Medicine, Faculty of Dentisty, Universitas Mahasaraswati Denpasar, Bali, Indonesia)



Article Info

Publish Date
30 Dec 2024

Abstract

Introduction. Oral Lichen Planus (OLP) is a chronic immunological disorder that is inflammatory in form. Unlike skin lesions, oral lesions are more resistant to local and systemic therapy. The aim of this literature review is to explain alternative therapies in OLP cases using intralesional injection techniques. Literature Review. In general, OLP lesions in the oral cavity have no symptoms, but the atrophic-erosive form has mild symptoms such as discomfort and soreness. OLP therapy can generally be carried out with systemic or local therapy, however, OLP therapy is a long-term therapy that can be a challenge of the treatment, particularly in complex medical patients. Discussion. The use of corticosteroids in oral diseases is generally as anti-inflammatory, anti-proliferative, and immunosuppressive. Various methods, such as topical and systemic corticosteroids, griseofulvin, topical retinoids, hyaluronic acid, tetracycline, and topical cyclosporine, have been used to reduce morbidity. From several previous studies, Triamcinolone acetonide injection is a corticosteroid commonly used in OLP therapy in varying doses. In general, Triamcinolone acetonide injection is given in a dose of 20mg/ml or 40mg/ml. Conclusion. Injectable corticosteroids, especially Triamcinolone acetonide, are an effective therapy as an OLP treatment that can minimize the side effects of long-term corticosteroid therapy.

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Journal Info

Abbrev

interdental

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Public Health

Description

Interdental Journal is a scientific published and supported by Faculty of Dentistry Universitas Mahasaraswati Denpasar and published Three Times a year. The submission process opens throughout the year. All submitted manuscript will be screened with double-blind peer review and editorial decision ...