Background: Operation or surgery is an invasive procedure to diagnose or treat disease, injury, or bodily disorders by making incisions that affect the patient's body and other organs. WHO reports an increase in the number of operations every year. The response that appears in preoperative patients is a psychological response in the form of anxiety. Murottal Al-Qur'an therapy can be used to overcome pre-operative anxiety. Objective: To determine the effect of Murotal Al-Qur'an therapy in reducing preoperative patient anxiety. Method: This scientific work uses the literature review method. Study Results: From the results of a review of 10 pieces of literature that met the inclusion and exclusion criteria, research results showed that there was an effect of Al-Qur'an murotal therapy on reducing preoperative patient anxiety. Conclusion: Al-Quran murotal therapy has an influence on reducing preoperative patient anxiety. Keywords: Murotal, Anxiety, Preoperative
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