Comparison of Molecular Testing Methods in Detecting Drug Resistance Tuberculosis

Yanika, Grevy
Alamanda, Cut Nur Cinthia
Rachman, Rifky Waluyajati

Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Vol. 31 No. 1 (2024)

Tuberculosis (TB) is the leading cause of infectious disease-related deaths in Indonesia, and the COVID-19 pandemic has led to a decline in TB reporting and an increase in Drug-Resistant Tuberculosis (DR-TB). While traditional culture and Drug Susceptibility Testing (DST) takes 2-8 weeks, therefore, genotypic assays such as GeneXpert, Line Probe Assay (LPA), and sequencing offer faster and more precise diagnosis and drug resistance information.