This research aims to discover how types of drugs are disguised through new types of modification and what strategies to overcome them. This research was carried out in 2 (two) provinces, Jakarta and North Sumatra. This research uses an empirical legal approach. Descriptive and evaluative qualitative data analysis techniques. Data collection techniques use interviews, focus group discussion (FGD), observation, and document study involving various parties: BNN, Health Service, Police, Pharmacists, and legal experts. The research results show that new physical active ingredients are already circulating in Indonesia, with the number of NPS circulating worldwide being 803 and 78 of them having entered Indonesia. 68 have been included in the attachment to the Law through Minister of Health Decree No. 20 of 2018, classified into eight groups. The rest cannot yet be detected, so their type has not been classified into any category. Furthermore, the reconstruction of the war strategy against new types of drugs (NPS) can be carried out in various ways, starting from rules/regulations, implementation of sanctions, the integrity of law enforcement, eradication, and prevention through the world of higher education, community involvement, and maximum activists, clusters and certification. Prisons for dealer abusers and victims, adequate budgets for law enforcement jobs, Special Rehabilitation Programs for NPS abusers, and creating a unique study institute that focuses on studying drug developments.
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