The purpose of this  research was to observe the quality of snake head fish bone powder using different boiling  temperature and NaOH concentration.The Factorial Randomized Block Design was used with two factors of treatment and 2 replications. The different boiling temperatures (60 0C, 650C, 700C) and three different NaOH concentrations (Control 0%, NaOH 2%, NaOH 4% and NaOH 6%). The parameters were yield, whiteness, density,  solubility and calcium content. The result showed that the treatments significantly effected the yield (43.98%-97.47%), whiteness (47.6-58.48%) density (0.51–0.67 g/ml), solubility(11.38-23.76%) and calcium content (16.86-22.77%).  Keyword :bone powder, snake head, calcium
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