Jurnal Farmasi Indonesia
Vol 21 No 2 (2024): Jurnal Farmasi Indonesia

Uji Aktivitas Antibakteri dan Sifat Fisik Gel Ekstrak Temulawak Terhadap Staphylococcus Aureus ATCC 25923

Maulana Nugraha (Unknown)
Ferli Eko K (Universitas Tidar, Magelang Indonesia)



Article Info

Publish Date
30 Nov 2024

Abstract

Temulawak (Curcuma zanthorrhiza) can be used as a traditional medicine. The use of temulawak directly on the skin is impractical and uncomfortable, so it is formulated in an emulgel dosage form. The test material is Temulawak powder extracted by maceration method with 96% ethanol solvent. The viscous extract of emulgel preparation and physical properties tested includes organoleptic, spreadability. Adhesion and pH. Antibacterial activity test against Staphylococcus aureus was carried out by using the well method. Antibacterial activity is indicated by the presence of an inhibitory zone on the emulgel with a concentration of 5%, 10% and 15%. The test results of the physical properties of Temulawak extract emulgel have good organoleptic, adhesion and pH, but the spreadability does not meet the good spreadability standards, because the diameter requirements for good dispersion for emulgel are 5 to 7 cm. And the results of the antibacterial activity test showed that the emulgel from Temulawak extract had antibacterial activity against Staphylocuccus aureus at concentrations of 5%, 10%, and 15%. With mean values of 15 mm, 17 mm and 19 mm, respectively. These results indicate that the Temulawak extract emulgel has antibacterial activity against Staphylococcus

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Journal Info

Abbrev

farmasi-indonesia

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Farmasi Indonesia (e-ISSN : 2302-4291 dan ISSN : 1693-8615) merupakan jurnal yang dikelola oleh Fakultas Farmasi, Universitas Setia Budi yang terbit sejak Februari 2004 dan terbit 2 kali dalam setahun yaitu periode bulan Maret dan November. Jurnal Farmasi Indonesia menerima naskah tentang ...