Asian Journal of Science, Technology, Engineering, and Art
Vol 3 No 1 (2025): Asian Journal of Science, Technology, Engineering, and Art

Dynamic Models of the Infection of Lassa Fever Epidemics Incorporating Detected and Undetected Class

Idi, Hamisu (Unknown)
Lasisi, Kazeem E. (Unknown)
Abdulhameed, M. (Unknown)
Kwami, A. M. (Unknown)
Muhammad, Muhammad Mubarak (Unknown)



Article Info

Publish Date
01 Feb 2025

Abstract

In the scope of this research endeavor, we embarked on the development of a dynamic model, intricately designed to scrutinize the intricate dynamics of Lassa fever transmission, encompassing both detected and undetected cases. Our central objective revolved around the meticulous examination of how a vaccine could exert its influence on the transmission dynamics of Lassa disease. The study encompassed an exhaustive exploration of the model's equilibrium states, diligently scrutinizing both disease-free and endemic equilibria. To shed light on the potential for disease spread, we calculated the pivotal epidemiological parameter, the basic reproduction number, employing the rigorous next-generation matrix methodology. Subsequently, we delved into a comprehensive stability analysis, encompassing both local and global stability assessments. The Routh-Hurwitz conditions were harnessed for local stability analysis, while the Castillo-Chavez criterion was leveraged for global stability analysis. In our quest for a profound understanding, we ventured into analytical techniques to derive exact solutions for the model, coupled with numerical computations facilitated by the versatile MATHEMATICA software. The culmination of our endeavors unveiled a compelling insight: the disease-free equilibrium attains local asymptotic stability if and only if the basic reproduction number assumes a value below unity; conversely, it stands as unstable when this threshold is exceeded. In essence, this implies that the complete eradication of Lassa fever is within reach when the secondary infection rate remains constrained below a critical threshold.

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Journal Info

Abbrev

AJSTEA

Publisher

Subject

Arts Computer Science & IT Engineering Social Sciences

Description

Asian Journal of Science, Technology, Engineering, and Art [3025-5287 (Print) and 3025-4507 (Online)] is a double-blind peer-reviewed, and open-access journal to disseminating all information contributing to the understanding and development of Science, Technology, Engineering, and Art. Its scope is ...