Eye health has a significant impact on quality of life, with more than 2.2 billion people experiencing vision problems. Many of these cases can be prevented or treated. The use of AI for eye disease classification helps healthcare professionals provide optimal care. However, the complexity of fundus images challenges classification performance. This study examines various Convolutional Neural Network (CNN) architectures using Transfer Learning and Adam optimization. Fundus images are processed using CLAHE (clip limit and grid size) and the Wiener filter (size) to enhance contrast and reduce noise. Afterward, ResNet-152, EfficientNet, MobileNetV1, and DenseNet-121 are tested to identify the most effective model. The study aims to determine the optimal CNN architecture for eye disease classification, assisting ophthalmologists in diagnosing eye diseases through fundus images. The best CNN model, ResNet-152, achieved an accuracy of 94.82%, outperforming other models by 3.95 - 8.29%.
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