Some complications that may occur in high-risk pregnancies, especially women who are pregnant at the age of more than 35 years, include the fetus in the womb experiencing genetic problems and congenital abnormalities. According to a number of theories, women at a greater age are at greater risk of having a baby born with genetic disorders. The purpose of this study was to analyze the relationship between knowledge and attitudes with a high risk of pregnancy at the age of more than 35 years in the working area of the Pulo Brayan Health Center, Medan. This type of research is an analytic survey using a cross-sectional approach by means of observation and data collection at one time. The statistical test used was the chi square test with a significance degree of p value 0.05 The results showed that 80% of mothers with less knowledge and 85% of negative attitudes experienced high-risk pregnancies, namely pregnant at age > 35 years. There is a significant relationship between knowledge and the risk of pregnancy over 35 years, p value 0.001 and there is an attitude relationship with the risk of pregnancy over 35 years, p value 0.000. Suggestions for the Puskesmas to optimize health education and proper handling of high-risk pregnancies
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