Medicosphere
Vol. 1 No. 4 (2024): J Divers Med Res 2024

The Role of Procalcitonin to Determine Infection in Diabetic Foot Ulcer: An Evidence-Based Case Report

Ardian, Laurentius Johan (Unknown)



Article Info

Publish Date
08 Oct 2024

Abstract

Introduction: Early diagnosis infection in diabetic foot patients remains challenging. Several biomarkers have been used as a diagnostic tool, including procalcitonin. However, the performance of this examination is still questioning. Aim: This evidence-based case report aims to assess the performance of procalcitonin level to distinguish between infected and non-infected diabetic foot. Method: Literature searching was performed in Medline, Cochrane, EBSCO, Scopus, and also hand searching. Only articles with cuts off outcome were included. Result: Patients with diabetic ulcer infection has a higher procalcitonin level compare with those who did not have a disease. Several cuts off provide to diagnose infection in the diabetic ulcer. Uzun et al. found 0.08 and 0.1 as a cut off which performed good specificity and sensitivity. Conclusion: Procalcitonin helps us to distinguish non-infected and infected diabetic ulcers. The best cut-off value was 0.5 with the 54 % sensitivity and 100 % specificity.

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Journal Info

Abbrev

medicosphere

Publisher

Subject

Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences

Description

Journal of Diverse Medical Research is an open access and peerreviewed journal published every month by Faculty of Medicine Universitas Pembangunan Nasional Veteran Jawa Timur. This journal is a dissemination medium for research result from various areas in medical ...