The purpose of this study is to examine the effect of profitability, asset structure, and company size on capital structure and growth opportunities. The population was taken from the manufacturing industry that was registered on the IDX for 2017-2021 as many as 179, and there were 74 companies that fulfilled purposive sampling. The analysis tool was performed using multiple linear regression. The results of the study concluded: (1). Return on assets has no effect on the debt to equity ratio, but has a positive and significant effect on the market to book value variable. (2). Tangibility assets have a positive and significant effect on the debt to equity ratio, but has no effect on the market to book value. (3). Ln total assets have no effect on either the debt to equity ratio or the market to book value
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