This study analyses the determination of the unit cost of inpatient room rates at PKU Muhammadiyah Nanggulan, Kripulonprogo-Yogyakarta by using the Activity-Based Costing (ABC) method. This research is quantitative research. The research data were obtained through interviews, documentation, and observation. Then, the data were analysed using a comparative descriptive analysis method with a quantitative approach. The results of the study showed that the determination of unit costs using the ABC system was higher than the traditional methods used by the hospital.
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